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Drug delivery to retina :A review

By: Shelke, D. A.
Contributor(s): Shirolkar, S.
Publisher: Mumbai Indian Drug Manufacture's Association - IDMA 2019Edition: Vol.56(6), Sep.Description: 7-21p.Subject(s): PHARMACEUTICSOnline resources: Click here In: Indian drugsSummary: The drug delivery to posterior segment especially to retina of eye is difficult due to various barriers. The diseases affecting the retina of eye are increasing and hence there is need to develop approaches for drug delivery to retina. This review describes the anatomy of retina, barriers associated with it, and diseases of retina. The drug delivery to retina by systemic, topical, intravitreal injection, intravitreal implant along with advance nanotechnology based and transporter mediated drug delivery is discussed here. The recent technologies in retinal drug delivery are also discussed to give comprehensive recent information about retinal drug delivery
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The drug delivery to posterior segment especially to retina of eye is difficult due to various barriers. The diseases affecting the retina of eye are increasing and hence there is need to develop approaches for drug delivery to retina. This review describes the anatomy of retina, barriers associated with it, and diseases of retina. The drug delivery to retina by systemic, topical, intravitreal injection, intravitreal implant along with advance nanotechnology based and transporter mediated drug delivery is discussed here. The recent technologies in retinal drug delivery are also discussed to give comprehensive recent information about retinal drug delivery

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